180519

• Gene Symbol: Mul1
• Gene Name: mitochondrial ubiquitin ligase activator of NFKB 1
• Gene Aliases: 0610009K11Rik, AV000801, Gide
• Chromosome Location: Chr.4: 138434661 - 138442265 on Build GRCm38
• UniGene ID: Mm.103413
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mul1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_026689.3	NP_080965.2	2, 3	304
GenBank mRNA	AK002416.1	-	2, 3	286
	AK044088.1	-	2, 3	266
	AK076419.1	-	2, 3	264
	AK083295.1	-	2, 3	275
	AK153956.1	-	2, 3	254
	AK170149.1	-	2, 3	288
	BC019516.1	-	2, 3	273	4163969
	BY062056.1	-	2, 3	295
	EU935009.1	-	2, 3	216

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_024544, BC014010, AK303820, AB097015, AK022937, and others.

Gene Ontology Categories:

Process(es)

mitochondrial fission
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
mitochondrion organization
activation of JUN kinase activity
negative regulation of mitochondrial fusion
regulation of mitochondrion organization
protein ubiquitination
negative regulation of cell growth
regulation of protein stability
protein destabilization
positive regulation of protein sumoylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of innate immune response
negative regulation of defense response to virus by host
protein stabilization
mitochondrion localization
regulation of mitochondrial membrane potential
negative regulation of protein kinase B signaling
negative regulation of type I interferon-mediated signaling pathway
cellular response to exogenous dsRNA
negative regulation of chemokine (C-C motif) ligand 5 production
positive regulation of mitochondrial fission
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
positive regulation of dendrite extension

Function(s)

ubiquitin-protein transferase activity
signal transducer activity
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
SUMO transferase activity
ubiquitin protein ligase binding
identical protein binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity