18159

• Gene Symbol: SETMAR
• Gene Name: SET domain and mariner transposase fusion gene
• Gene Aliases: METNASE, Mar1
• Chromosome Location: Chr.3: 4303304 - 4320649 on Build GRCh38
• UniGene ID: Hs.475300
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SETMAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001276325.1	NP_001263254.1	2	687
	NM_006515.3	NP_006506.3	2	687
	XM_017007032.1	XP_016862521.1	2	750
GenBank mRNA	AF054989.1	-	2	613
	AK222734.1	-	2	623
	AK307537.1	-	2	687
	AK311418.1	-	2	719
	AY952295.1	-	2	592
	BC011635.2	-	2	613	4080032
	U80776.1	-	2	604

More Information

Panther Classification:

Molecular Function -

viral or transposable element protein, histone modifying enzyme

Gene Ontology Categories:

Process(es)

DNA double-strand break processing
DNA catabolic process, endonucleolytic
double-strand break repair via nonhomologous end joining
cell proliferation
histone H3-K36 methylation
DNA integration
replication fork processing
mitotic DNA integrity checkpoint
histone H3-K4 methylation
negative regulation of cell cycle arrest
nucleic acid phosphodiester bond hydrolysis
histone H3-K36 dimethylation
positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
positive regulation of double-strand break repair via nonhomologous end joining
negative regulation of chromosome organization

Function(s)

single-stranded DNA endodeoxyribonuclease activity
double-stranded DNA binding
single-stranded DNA binding
endonuclease activity
protein binding
zinc ion binding
histone methyltransferase activity (H3-K4 specific)
protein homodimerization activity
structure-specific DNA binding
DNA topoisomerase binding
histone methyltransferase activity (H3-K36 specific)