183017

• Gene Symbol: Aptx
• Gene Name: aprataxin
• Gene Aliases: 2410016G21Rik, AA388047, FHA-HIT
• Chromosome Location: Chr.4: 40682078 - 40721667 on Build GRCm38
• UniGene ID: Mm.430710
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Aptx
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001025444.3	NP_001020615.1	7, 8	926
	NM_001025445.2	NP_001020616.1	7, 8	921
	NM_025545.4	NP_079821.3	7, 8	1061
GenBank mRNA	AK005286.1	-	6, 7	878
	AK010516.1	-	7, 8	908
	AK017522.1	-	6, 7	889
	AK077351.1	-	7, 8	1062
	AK088928.1	-	6, 7	611
	AY040780.1	-	7, 8	1072
	AY208844.1	-	7, 8	1073
	BC021872.1	-	7, 8	919	3994375
	BC068309.1	-	6, 7	834
	BC071213.1	-	7, 8	913

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_148889, XM_008763607, XM_006238028, XM_006238027, XM_006238026, and others.

Panther Classification:

Molecular Function -

damaged DNA-binding protein

Gene Ontology Categories:

Process(es)

single strand break repair
DNA ligation
DNA repair
double-strand break repair
cellular response to DNA damage stimulus
dephosphorylation
regulation of protein stability
response to hydrogen peroxide
nucleic acid phosphodiester bond hydrolysis
polynucleotide 3' dephosphorylation

Function(s)

DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
double-stranded RNA binding
catalytic activity
GPI-anchor transamidase activity
phosphoglycolate phosphatase activity
hydrolase activity
DNA 5'-adenosine monophosphate hydrolase activity
polynucleotide 3'-phosphatase activity
metal ion binding
protein N-terminus binding
phosphoprotein binding
coenzyme F390-A hydrolase activity
coenzyme F390-G hydrolase activity