18319

• Gene Symbol: MTHFD2
• Gene Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
• Gene Aliases: NMDMC
• Chromosome Location: Chr.2: 74198563 - 74215298 on Build GRCh38
• UniGene ID: Hs.469030
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MTHFD2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006636.3	NP_006627.2	4	543
	NR_027405.1		5	641
	XM_006711924.2	XP_006711987.1	3	330
GenBank mRNA	AK130664.1	-	4	491
	AK222826.1	-	4	493
	AK223041.1	-	4	491
	AK300035.1	-	3	308
	AK302245.1	-	2	183
	AK313138.1	-	4	491
	AU125762.1	-	4	522
	BC001548.1	-	4	478	3462450
	BC015062.1	-	5	591	4285669
	BC017054.1	-	4	471	3846710
	BX475613.1	-	4	544
	X16396.1	-	4	461

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001109398, FQ234580.
This siRNA also targets the following transcripts in Mouse: NM_008638, AK076019, AK159680, AK199322, AK166262, and others.

Gene Ontology Categories:

Process(es)

one-carbon metabolic process
folic acid-containing compound biosynthetic process
tetrahydrofolate metabolic process
folic acid metabolic process
oxidation-reduction process

Function(s)

magnesium ion binding
formate-tetrahydrofolate ligase activity
methenyltetrahydrofolate cyclohydrolase activity
methylenetetrahydrofolate dehydrogenase (NAD+) activity
methylenetetrahydrofolate dehydrogenase (NADP+) activity
phosphate ion binding