184459

• Gene Symbol: Iqgap1
• Gene Name: IQ motif containing GTPase activating protein 1
• Gene Aliases: AA682088, D7Ertd237e, D7Ertd257e, mKIAA0051
• Chromosome Location: Chr.7: 80711583 - 80815545 on Build GRCm38
• UniGene ID: Mm.207619
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Iqgap1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_016721.2	NP_057930.2	32, 33	4292
GenBank mRNA	AF240630.1	-	32, 33	4255
	AK029631.1	-	14, 15	1989
	AK077354.1	-	8, 9	1217
	AK129044.1	-	32, 33	4230
	AK154213.1	-	7, 8	1007
	AK160892.1	-	14, 15	1827
	BC046385.1	-	32, 33	4210	3256630

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108489, BC169057.

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, GTPase-activating protein

Gene Ontology Categories:

Process(es)

regulation of cytokine production
signal transduction
epidermal growth factor receptor signaling pathway
small GTPase mediated signal transduction
fibroblast growth factor receptor signaling pathway
negative regulation of dephosphorylation
cellular response to platelet-derived growth factor stimulus
regulation of GTPase activity
cellular response to fibroblast growth factor stimulus
positive regulation of protein kinase activity
platelet-derived growth factor receptor signaling pathway
cellular response to calcium ion
cellular response to epidermal growth factor stimulus
positive regulation of protein serine/threonine kinase activity
neuron projection extension

Function(s)

GTPase activator activity
protein binding
calmodulin binding
phosphatidylinositol-3,4,5-trisphosphate binding
Rho GTPase binding
protein kinase binding
protein phosphatase binding
protein complex binding
protein serine/threonine kinase activator activity
Rac GTPase binding