184587

• Gene Symbol: Irf3
• Gene Name: interferon regulatory factor 3
• Gene Aliases: C920001K05Rik, IRF-3
• Chromosome Location: Chr.7: 44997648 - 45002848 on Build GRCm38
• UniGene ID: Mm.3960
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Irf3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_016849.4	NP_058545.1	8	1422
GenBank mRNA	AK013944.1	-	8	1413
	AK145977.1	-	8	1555
	AK146378.1	-	8	1401
	AK151750.1	-	8	1402
	AK152689.1	-	8	1402
	BC003233.1	-	7	1479
	BC023244.1	-	7	1646
	BC050882.1	-	8	1284	5690948
	U75839.1	-	8	1396
	U75840.1	-	8	1279

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001006969, XM_006229021, XM_008759337, XM_006229022, XM_006229024, and others.

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
immune system process
transcription, DNA-templated
regulation of transcription, DNA-templated
response to bacterium
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to exogenous dsRNA
innate immune response
type I interferon biosynthetic process
negative regulation of interferon-beta biosynthetic process
negative regulation of defense response to virus by host
positive regulation of cytokine secretion
defense response to virus
positive regulation of type I interferon-mediated signaling pathway
cellular response to lipopolysaccharide
programmed necrotic cell death

Function(s)

regulatory region DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
identical protein binding
protein homodimerization activity
transcription regulatory region DNA binding