185417

• Gene Symbol: Pias1
• Gene Name: protein inhibitor of activated STAT 1
• Gene Aliases: 2900068C24Rik, Ddxbp1, GBP
• Chromosome Location: Chr.9: 62878366 - 62980879 on Build GRCm38
• UniGene ID: Mm.431253
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pias1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019663.3	NP_062637.2	3, 4	564
GenBank mRNA	AF077950.1	-	3, 4	556
	AK075708.1	-	3, 4	565
	AK153871.1	-	3, 4	569
	BC051417.1	-	3, 4	561	6515027

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106829, AY644724.

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
JAK-STAT cascade
protein sumoylation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of protein sumoylation
regulation of cell proliferation
negative regulation of apoptotic process
fat cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of smooth muscle cell differentiation
protein-DNA complex assembly
negative regulation of nucleic acid-templated transcription

Function(s)

DNA binding
transcription corepressor activity
protein binding
protein C-terminus binding
transcription factor binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
SUMO transferase activity
enzyme binding
protein domain specific binding
ubiquitin protein ligase binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
SUMO ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity