185518

• Gene Symbol: Foxo3
• Gene Name: forkhead box O3
• Gene Aliases: 1110048B16Rik, 2010203A17Rik, C76856, FKHRL1, Fkhr2, Foxo3a
• Chromosome Location: Chr.10: 42181845 - 42276746 on Build GRCm38
• UniGene ID: Mm.338613
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Foxo3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019740.2	NP_062714.1	3	2060
GenBank mRNA	AF114259.1	-	3	2060
	AK047413.1	-	3	2018
	AK139629.1	-	3	2049

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001455, NM_201559, AK092357, BC021224, AK301304, and others.
This siRNA also targets the following transcripts in Rat: NM_001106395.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ovulation from ovarian follicle
initiation of primordial ovarian follicle growth
antral ovarian follicle growth
oocyte maturation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
regulation of translation
apoptotic process
anatomical structure morphogenesis
cell differentiation
DNA damage response, signal transduction by p53 class mediator
cellular response to oxidative stress
glucose homeostasis
positive regulation of neuron apoptotic process
positive regulation of erythrocyte differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of canonical Wnt signaling pathway
neuronal stem cell population maintenance
extrinsic apoptotic signaling pathway in absence of ligand
regulation of neural precursor cell proliferation
regulation of reactive oxygen species metabolic process

Function(s)

core promoter binding
transcription cofactor binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein kinase binding
chromatin DNA binding
sequence-specific DNA binding