185897

• Gene Symbol: Mtor
• Gene Name: mechanistic target of rapamycin (serine/threonine kinase)
• Gene Aliases: 2610315D21Rik, AI327068, FRAP, FRAP2, Frap1, RAFT1, RAPT1, flat
• Chromosome Location: Chr.4: 148448582 - 148557685 on Build GRCm38
• UniGene ID: Mm.21158
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mtor
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_020009.2	NP_064393.2	21	3277
GenBank mRNA	AF152838.1	-	21	3252
	AK143381.1	-	18	2688
	BC112904.1	-	21	3235	6465126

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019906, L37085, U11681.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

double-strand break repair via homologous recombination
positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
regulation of glycogen biosynthetic process
regulation of carbohydrate metabolic process
protein phosphorylation
response to stress
germ cell development
negative regulation of autophagy
positive regulation of lamellipodium assembly
positive regulation of gene expression
positive regulation of myotube differentiation
cell growth
negative regulation of macroautophagy
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
cell projection organization
positive regulation of actin filament polymerization
ruffle organization
regulation of myelination
cellular response to nutrient levels
TOR signaling
regulation of fatty acid beta-oxidation
regulation of response to food
response to insulin
regulation of actin cytoskeleton organization
regulation of GTPase activity
response to amino acid
regulation of carbohydrate utilization
regulation of osteoclast differentiation
positive regulation of translation
negative regulation of cell size
regulation of protein kinase activity
positive regulation of transcription from RNA polymerase III promoter
protein autophosphorylation
positive regulation of lipid biosynthetic process
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of stress fiber assembly
negative regulation of NFAT protein import into nucleus
positive regulation of protein kinase B signaling
cellular response to hypoxia

Function(s)

nucleotide binding
RNA polymerase III type 1 promoter DNA binding
RNA polymerase III type 2 promoter DNA binding
RNA polymerase III type 3 promoter DNA binding
TFIIIC-class transcription factor binding
protein serine/threonine kinase activity
protein binding
ATP binding
drug binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphotransferase activity, alcohol group as acceptor
protein domain specific binding
ribosome binding
protein dimerization activity
phosphoprotein binding