186283

• Gene Symbol: Fbxw7
• Gene Name: F-box and WD-40 domain protein 7
• Gene Aliases: 1110001A17Rik, AGO, Cdc4, Fbw7, Fbwd6, Fbx30, Fbxo30, Fbxw6, SEL-10
• Chromosome Location: Chr.3: 84815577 - 84979198 on Build GRCm38
• UniGene ID: Mm.196475
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fbxw7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_080428.3	NP_536353.2	1	280
GenBank mRNA	AB221593.1	-	1	122
	AF391192.1	-	1	280
	AF427101.1	-	1	202
	BC131648.1	-	1	144	40110349

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_003749311.

Gene Ontology Categories:

Process(es)

vasculogenesis
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
sister chromatid cohesion
Notch signaling pathway
protein ubiquitination
lung development
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
positive regulation of protein ubiquitination
negative regulation of DNA endoreduplication
cellular response to UV
positive regulation of epidermal growth factor-activated receptor activity
protein stabilization
positive regulation of ubiquitin-protein transferase activity
positive regulation of ERK1 and ERK2 cascade
positive regulation of proteasomal protein catabolic process
regulation of mitophagy
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
positive regulation of protein targeting to mitochondrion
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

transcription factor activity, sequence-specific DNA binding
protein binding
cyclin binding
protein binding, bridging
ubiquitin protein ligase binding
identical protein binding
ubiquitin-protein transferase activator activity