186560

• Gene Symbol: Map3k8
• Gene Name: mitogen-activated protein kinase kinase kinase 8
• Gene Aliases: Cot, Cot/Tpl2, Est, Estf, Tpl-2, Tpl2, c-COT
• Chromosome Location: Chr.18: 4331325 - 4353481 on Build GRCm38
• UniGene ID: Mm.3275
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map3k8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007746.2	NP_031772.1	2	228
GenBank mRNA	AK041009.1	-	2	230
	AK140334.1	-	2	229
	AK149624.1	-	2	229
	AK149846.1	-	2	229
	AK157123.1	-	2	195
	AK171403.1	-	2	233
	BC125286.1	-	1	129	40129801
	BC137922.1	-	1	129	8860941
	D13759.1	-	2	228

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053847, XM_006254048, M94454, FQ217924.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

immune system process
protein phosphorylation
cell cycle
signal transduction
regulation of mitotic cell cycle
phosphorylation
signal transduction by protein phosphorylation
stress-activated protein kinase signaling cascade
activation of protein kinase activity
regulation of apoptotic process

Function(s)

nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding