186568

• Gene Symbol: Map3k5
• Gene Name: mitogen-activated protein kinase kinase kinase 5
• Gene Aliases: 7420452D20Rik, ASK, ASK1, MAPKKK5, Mekk5
• Chromosome Location: Chr.10: 19934513 - 20142750 on Build GRCm38
• UniGene ID: Mm.6595
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map3k5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008580.4	NP_032606.4	9, 10	1631
GenBank mRNA	AB006787.3	-	9, 10	1683
	BC116627.1	-	9, 10	1631	40086293
	BC116628.1	-	8, 9	1607	40086299
	BC133697.1	-	9, 10	1631	40086283

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001277694, XM_008758622.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
activation of MAPK activity
positive regulation of protein phosphorylation
immune system process
protein phosphorylation
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
JNK cascade
intrinsic apoptotic signaling pathway in response to oxidative stress
regulation of cell death
phosphorylation
response to endoplasmic reticulum stress
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of JUN kinase activity
innate immune response
positive regulation of JNK cascade
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to hydrogen peroxide
programmed necrotic cell death
positive regulation of neuron death
cellular response to reactive nitrogen species

Function(s)

nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
cysteine-type endopeptidase activator activity involved in apoptotic process
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein phosphatase binding
protein homodimerization activity
metal ion binding