186834

• Gene Symbol: Traf2
• Gene Name: TNF receptor-associated factor 2
• Gene Aliases: AI325259
• Chromosome Location: Chr.2: 25517982 - 25546940 on Build GRCm38
• UniGene ID: Mm.3399
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Traf2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001290413.1	NP_001277342.1	5, 6	667
	NM_009422.3	NP_033448.2	5, 6	646
GenBank mRNA	AF027570.1	-	4, 5	558
	AK038136.1	-	5, 6	595
	AK052934.1	-	5, 6	595
	AK151653.1	-	5, 6	584
	AK152174.1	-	5, 6	614
	AK159581.1	-	5, 6	616
	AK159585.1	-		593
	BC003801.1	-	4, 5	572	3492839
	L35303.1	-	5, 6	583

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of T cell cytokine production
protein complex assembly
apoptotic process
signal transduction
activation of NF-kappaB-inducing kinase activity
protein catabolic process
positive regulation of interleukin-2 production
tumor necrosis factor-mediated signaling pathway
negative regulation of glial cell apoptotic process
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JUN kinase activity
cellular protein complex assembly
regulation of JNK cascade
regulation of immunoglobulin secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
protein autoubiquitination
protein homotrimerization
protein K63-linked ubiquitination
cellular response to nitric oxide
positive regulation of protein homodimerization activity
programmed necrotic cell death
positive regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of I-kappaB phosphorylation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

ubiquitin-protein transferase activity
receptor binding
tumor necrosis factor receptor binding
CD40 receptor binding
protein binding
zinc ion binding
lipid binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
enzyme binding
protein kinase binding
protein phosphatase binding
mitogen-activated protein kinase kinase kinase binding
ubiquitin protein ligase binding
thioesterase binding
protein complex binding
identical protein binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
sphingolipid binding
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity