187238

• Gene Symbol: Tfap2a
• Gene Name: transcription factor AP-2, alpha
• Gene Aliases: AP-2, AP2alpha, Ap-2 (a), Ap2, Ap2tf, Tcfap2a
• Chromosome Location: Chr.13: 40713802 - 40738238 on Build GRCm38
• UniGene ID: Mm.487150
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tfap2a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001122948.2	NP_001116420.1	3	874
	NM_001301674.1	NP_001288603.1	4	853
	NM_011547.4	NP_035677.2	3	609
GenBank mRNA	AB221578.1	-	3	500
	AK013900.1	-	1	30
	AK053704.1	-	3	859
	AK081627.1	-	3	619
	AK140956.1	-	3	620
	AK145772.1	-	3	564
	BC007471.1	-	3	584	3497082
	BC018226.1	-	4	852	3983850
	U17285.1	-	3	601
	U17286.1	-	2	80
	U17287.1	-	3	838
	U17288.1	-	2	623
	X74216.1	-	3	570

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003220, NM_001042425, NM_001032280, BC017754, X52611, and others.
This siRNA also targets the following transcripts in Rat: NM_001107345, XM_008771570.

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
kidney development
neural tube closure
lens morphogenesis in camera-type eye
outflow tract morphogenesis
keratinocyte development
optic vesicle morphogenesis
optic cup structural organization
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
sensory perception of sound
negative regulation of cell proliferation
embryonic pattern specification
embryonic body morphogenesis
positive regulation of gene expression
negative regulation of transcription by competitive promoter binding
neural crest cell development
anterior neuropore closure
trigeminal nerve development
oculomotor nerve formation
forebrain neuron development
positive regulation of cell migration
positive regulation of bone mineralization
response to lipopolysaccharide
embryonic forelimb morphogenesis
forelimb morphogenesis
negative regulation of epidermal growth factor receptor signaling pathway
inner ear morphogenesis
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
skin development
regulation of cell differentiation
regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
sympathetic nervous system development
embryonic camera-type eye morphogenesis
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
epidermis morphogenesis
palate development
lens induction in camera-type eye
face morphogenesis
bone morphogenesis
eyelid development in camera-type eye
cornea development in camera-type eye
positive regulation of tooth mineralization
cellular response to iron ion
basement membrane organization
negative regulation of reactive oxygen species metabolic process

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
RNA polymerase II transcription corepressor activity
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity