187587

• Gene Symbol: Wfs1
• Gene Name: Wolfram syndrome 1 homolog (human)
• Gene Aliases: AI481085, wolframin
• Chromosome Location: Chr.5: 36966104 - 36988982 on Build GRCm38
• UniGene ID: Mm.20916
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Wfs1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011716.2	NP_035846.1	8	1141
GenBank mRNA	AF084482.1	-	8	1074
	AJ011971.1	-	8	1068
	AK145023.1	-	8	1113
	AK170180.1	-	8	1096
	AK179248.1	-	1	84
	BC046988.1	-	8	1077	6492038

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031823, AF136378.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
kidney development
renal water homeostasis
visual perception
sensory perception of sound
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
positive regulation of protein ubiquitination
endoplasmic reticulum calcium ion homeostasis
response to endoplasmic reticulum stress
glucose homeostasis
negative regulation of programmed cell death
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of neuron apoptotic process
positive regulation of growth
protein stabilization
neurological system process
positive regulation of protein metabolic process
regulation of cell cycle
positive regulation of calcium ion transport
calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of ATF6-mediated unfolded protein response
negative regulation of type B pancreatic cell apoptotic process

Function(s)

calmodulin binding
ubiquitin protein ligase binding
activating transcription factor binding
calcium-dependent protein binding
ATPase binding