188094

• Gene Symbol: Mapk1
• Gene Name: mitogen-activated protein kinase 1
• Gene Aliases: 9030612K14Rik, AA407128, AU018647, C78273, ERK, Erk2, MAPK2, PRKM2, Prkm1, p41mapk, p42mapk
• Chromosome Location: Chr.16: 16983382 - 17047453 on Build GRCm38
• UniGene ID: Mm.196581
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mapk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001038663.1	NP_001033752.1	4, 5	856
	NM_011949.3	NP_036079.1	4, 5	856
GenBank mRNA	AK035386.1	-	4, 5	830
	AK048127.1	-	4, 5	858
	AK087925.1	-	4, 5	831
	AK132241.1	-	4, 5	844
	AK148853.1	-	4, 5	836
	AK193200.1	-	1, 2	47
	AK210736.1	-	1, 2	47
	BC058258.1	-	4, 5	799	6468233
	D10939.1	-	4, 5	671
	X58712.1	-	4, 5	629

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053842, XM_006248659, XM_006248658, XM_008768848, M64300, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
MAPK import into nucleus
transcription, DNA-templated
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
cell cycle
signal transduction
response to toxic substance
organ morphogenesis
positive regulation of peptidyl-threonine phosphorylation
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
sensory perception of pain
cytosine metabolic process
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
regulation of stress-activated MAPK cascade
mammary gland epithelial cell proliferation
intracellular signal transduction
ERBB signaling pathway
response to exogenous dsRNA
response to estrogen
negative regulation of cell differentiation
positive regulation of translation
T cell receptor signaling pathway
B cell receptor signaling pathway
regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
long-term synaptic potentiation
lung morphogenesis
trachea formation
labyrinthine layer blood vessel development
ERK1 and ERK2 cascade
response to epidermal growth factor
cellular response to organic substance
caveolin-mediated endocytosis
regulation of Golgi inheritance
cellular response to granulocyte macrophage colony-stimulating factor stimulus
regulation of early endosome to late endosome transport

Function(s)

nucleotide binding
phosphotyrosine binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
transcription factor binding
RNA polymerase II carboxy-terminal domain kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
phosphatase binding
mitogen-activated protein kinase kinase kinase binding