188104

• Gene Symbol: Mapk3
• Gene Name: mitogen-activated protein kinase 3
• Gene Aliases: Erk-1, Erk1, Ert2, Esrk1, Mnk1, Mtap2k, Prkm3, p44, p44erk1, p44mapk
• Chromosome Location: Chr.7: 126759626 - 126765816 on Build GRCm38
• UniGene ID: Mm.8385
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mapk3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011952.2	NP_036082.1	9	1599
GenBank mRNA	AK155287.1	-	8	1541
	BC013754.1	-	9	1432
	BC029712.1	-	9	1593	5041517
	Z14249.1	-	9	1569

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017347, S46779, U12008, M61177, M38194.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
MAPK import into nucleus
positive regulation of protein phosphorylation
transcription, DNA-templated
protein complex assembly
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
cell cycle
signal transduction
response to toxic substance
organ morphogenesis
phosphorylation
peptidyl-serine phosphorylation
sensory perception of pain
BMP signaling pathway
positive regulation of cyclase activity
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
regulation of stress-activated MAPK cascade
positive regulation of histone phosphorylation
positive regulation of histone acetylation
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
response to exogenous dsRNA
positive regulation of translation
positive regulation of transcription from RNA polymerase II promoter
regulation of sequence-specific DNA binding transcription factor activity
cartilage development
regulation of cytoskeleton organization
lung morphogenesis
trachea formation
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
interleukin-1-mediated signaling pathway
response to epidermal growth factor
caveolin-mediated endocytosis
regulation of Golgi inheritance
regulation of early endosome to late endosome transport
negative regulation of apolipoprotein binding

Function(s)

nucleotide binding
phosphotyrosine binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphatase binding
scaffold protein binding