188593

• Gene Symbol: Xbp1
• Gene Name: X-box binding protein 1
• Gene Aliases: D11Ertd39e, TREB-5, TREB5, XBP-1
• Chromosome Location: Chr.11: 5520641 - 5525993 on Build GRCm38
• UniGene ID: Mm.469937
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Xbp1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001271730.1	NP_001258659.1	6	1092
	NM_013842.3	NP_038870.2	5	1118
GenBank mRNA	AF027963.3	-	5	792
	AF443192.1	-	6	1092
	AK145241.1	-	5	779
	AK178083.1	-	2	288
	AK183866.1	-	2	221
	AK187998.1	-	2	288
	AK191275.1	-	2	288
	AK195676.1	-	2	293
	AK201525.1	-	2	277
	AK202632.1	-	2	305
	AK204892.1	-	2	314
	AK206627.1	-	2	288
	AK206863.1	-	2	289
	AK207925.1	-	2	303
	AK209182.1	-	2	288
	AK211765.1	-	2	303
	AK213043.1	-	2	303
	AK216856.1	-	2	286
	AK217319.1	-	2	288
	AK217907.1	-	2	288
	AK218355.1	-	2	288
	AK218387.1	-	2	287
	AK218413.1	-	2	288
	AK219822.1	-	1	317
	BC003496.1	-	1	248
	BC008153.1	-	5	733
	BC016079.1	-	5	1012	4489182
	BC029197.1	-	5	773	2648085

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001271731, NM_001004210, CB691171, BC079450.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
liver development
positive regulation of protein phosphorylation
endothelial cell proliferation
epithelial cell maturation
positive regulation of immunoglobulin production
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
lipid metabolic process
transport
autophagy
apoptotic process
response to unfolded protein
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
multicellular organism development
muscle organ development
regulation of autophagy
positive regulation of autophagy
negative regulation of myotube differentiation
phosphatidylinositol 3-kinase signaling
protein transport
cell growth
cell differentiation
endoplasmic reticulum unfolded protein response
exocrine pancreas development
positive regulation of histone methylation
regulation of protein stability
protein destabilization
cellular response to nutrient
positive regulation of TOR signaling
cellular response to insulin stimulus
cellular response to oxidative stress
response to endoplasmic reticulum stress
cellular triglyceride homeostasis
cellular response to vascular endothelial growth factor stimulus
cellular response to glucose starvation
response to drug
glucose homeostasis
cholesterol homeostasis
positive regulation of transcription factor import into nucleus
negative regulation of apoptotic process
positive regulation of MHC class II biosynthetic process
positive regulation of B cell differentiation
positive regulation of T cell differentiation
positive regulation of fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
vascular endothelial growth factor receptor signaling pathway
neuron development
positive regulation of immunoglobulin secretion
response to electrical stimulus
fatty acid homeostasis
sterol homeostasis
serotonin secretion, neurotransmission
adipose tissue development
epithelial cell maturation involved in salivary gland development
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to fructose stimulus
cellular response to glucose stimulus
cellular response to interleukin-4
cellular response to peptide hormone stimulus
cellular response to fluid shear stress
cellular response to laminar fluid shear stress
positive regulation of plasma cell differentiation
negative regulation of endoplasmic reticulum unfolded protein response
positive regulation of endoplasmic reticulum unfolded protein response
positive regulation of proteasomal protein catabolic process
positive regulation of protein acetylation
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of lactation
response to insulin-like growth factor stimulus
positive regulation of hepatocyte proliferation
positive regulation of endothelial cell apoptotic process
positive regulation of interleukin-6 secretion

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter binding
RNA polymerase II transcription factor binding
enhancer sequence-specific DNA binding
protease binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein kinase binding
chromatin DNA binding
ubiquitin protein ligase binding
phosphatidylinositol 3-kinase regulatory subunit binding
histone deacetylase binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity