189705

• Gene Symbol: Alox15
• Gene Name: arachidonate 15-lipoxygenase
• Gene Aliases: 12-LOX, 15-LOX, Alox12, Alox12l
• Chromosome Location: Chr.10: 56953692 - 56962140 on Build Rnor_6.0
• UniGene ID: Rn.11318
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Alox15
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031010.2	NP_112272.2	2	278
	XM_006246823.2	XP_006246885.1	4	559
	XM_006246824.2	XP_006246886.1	3	454
GenBank mRNA	L06040.1	-	2	291
	S69383.1	-	2	278

More Information

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

ossification
negative regulation of adaptive immune response
phosphatidylethanolamine biosynthetic process
positive regulation of cell proliferation
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
bone mineralization
positive regulation of cell growth
positive regulation of actin filament polymerization
positive regulation of heterotypic cell-cell adhesion
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
regulation of membrane potential
negative regulation of apoptotic process
apoptotic cell clearance
negative regulation of cell volume
icosanoid biosynthetic process
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
phosphatidylinositol-4,5-bisphosphate binding
potassium channel inhibitor activity
hepoxilin-epoxide hydrolase activity
arachidonate 15-lipoxygenase activity
hepoxilin A3 synthase activity