190280

• Gene Symbol: Ptch1
• Gene Name: patched 1
• Gene Aliases: Ptch, Ptch2
• Chromosome Location: Chr.17: 1032242 - 1085885 on Build Rnor_6.0
• UniGene ID: Rn.102312
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptch1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053566.1	NP_446018.1	23	4247
GenBank mRNA	AY357891.1	-	23	4247

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
branching involved in ureteric bud morphogenesis
in utero embryonic development
cell fate determination
neural tube formation
neural tube closure
heart morphogenesis
signal transduction
smoothened signaling pathway
regulation of mitotic cell cycle
pattern specification process
brain development
negative regulation of cell proliferation
epidermis development
regulation of smoothened signaling pathway
response to mechanical stimulus
organ morphogenesis
dorsal/ventral pattern formation
epidermal cell fate specification
response to chlorate
positive regulation of cholesterol efflux
response to organic cyclic compound
protein processing
spinal cord motor neuron differentiation
neural tube patterning
dorsal/ventral neural tube patterning
neural plate axis specification
embryonic limb morphogenesis
mammary gland development
response to estradiol
response to retinoic acid
regulation of protein localization
limb morphogenesis
hindlimb morphogenesis
regulation of growth
negative regulation of multicellular organism growth
regulation of cell proliferation
response to drug
glucose homeostasis
negative regulation of sequence-specific DNA binding transcription factor activity
keratinocyte proliferation
positive regulation of epidermal cell differentiation
negative regulation of osteoblast differentiation
negative regulation of smoothened signaling pathway
embryonic organ development
negative regulation of epithelial cell proliferation
negative regulation of cell division
pharyngeal system development
mammary gland duct morphogenesis
mammary gland epithelial cell differentiation
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
cell differentiation involved in kidney development
somite development
cellular response to cholesterol
renal system development
cell proliferation involved in metanephros development
protein targeting to plasma membrane

Function(s)

molecular_function
patched binding
smoothened binding
hedgehog receptor activity
heparin binding
cholesterol binding
cyclin binding
protein complex binding
hedgehog family protein binding