190577

• Gene Symbol: Ptpn2
• Gene Name: protein tyrosine phosphatase, non-receptor type 2
• Gene Aliases: -
• Chromosome Location: Chr.18: 63415298 - 63489266 on Build Rnor_6.0
• UniGene ID: Rn.33497
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptpn2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053990.1	NP_446442.1	6	600
	XM_006254854.2	XP_006254916.1	6	1839
	XM_006254855.2	XP_006254917.1	6	1839
	XM_008772080.1	XP_008770302.1	6	1839
	XM_008772081.1	XP_008770303.1	6	1839
GenBank mRNA	BC078758.1	-	6	639	7132485
	X58828.1	-	6	600

More Information

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

protein dephosphorylation
negative regulation of cell proliferation
insulin receptor signaling pathway
negative regulation of tumor necrosis factor-mediated signaling pathway
negative regulation of lipid storage
B cell differentiation
T cell differentiation
erythrocyte differentiation
peptidyl-tyrosine dephosphorylation
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tyrosine phosphorylation of Stat1 protein
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of tyrosine phosphorylation of Stat6 protein
glucose homeostasis
negative regulation of macrophage differentiation
positive regulation of gluconeogenesis
negative regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
negative regulation of T cell receptor signaling pathway
negative regulation of chemotaxis
negative regulation of interferon-gamma-mediated signaling pathway
negative regulation of type I interferon-mediated signaling pathway
negative regulation of interleukin-6-mediated signaling pathway
negative regulation of ERK1 and ERK2 cascade
regulation of hepatocyte growth factor receptor signaling pathway
negative regulation of interleukin-2-mediated signaling pathway
negative regulation of prolactin signaling pathway
negative regulation of interleukin-4-mediated signaling pathway
negative regulation of macrophage colony-stimulating factor signaling pathway
negative regulation of positive thymic T cell selection
negative regulation of platelet-derived growth factor receptor-beta signaling pathway

Function(s)

DNA binding
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
integrin binding
protein kinase binding
syntaxin binding
receptor tyrosine kinase binding