191926

• Gene Symbol: Erbb4
• Gene Name: v-erb-b2 avian erythroblastic leukemia viral oncogene 4
• Gene Aliases: -
• Chromosome Location: Chr.9: 75021790 - 76178936 on Build Rnor_6.0
• UniGene ID: Rn.163078
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Erbb4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021687.1	NP_067719.1	3, 4	455
GenBank mRNA	AF041838.1	-	3, 4	455
	AY375306.1	-	3, 4	422
	AY375307.1	-	3, 4	422
	AY375308.1	-	3, 4	422

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010154, AK144050.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

neural crest cell migration
transcription, DNA-templated
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
nervous system development
heart development
lactation
positive regulation of cell proliferation
negative regulation of cell proliferation
embryonic pattern specification
negative regulation of muscle cell apoptotic process
cell migration
peptidyl-tyrosine phosphorylation
telencephalon development
central nervous system morphogenesis
olfactory bulb interneuron differentiation
signal transduction by protein phosphorylation
regulation of cell migration
positive regulation of cell migration
mammary gland development
positive regulation of synaptic transmission, GABAergic
response to progesterone
odontogenesis
response to drug
positive regulation of tyrosine phosphorylation of Stat5 protein
response to hydrogen peroxide
negative regulation of apoptotic process
surfactant homeostasis
positive regulation of phosphatidylinositol 3-kinase activity
mitochondrial fragmentation involved in apoptotic process
cell fate commitment
positive regulation of transcription, DNA-templated
positive regulation of glucose import
protein autophosphorylation
positive regulation of epithelial cell proliferation
positive regulation of cardiac muscle cell proliferation
synapse maturation
mammary gland epithelial cell differentiation
mammary gland alveolus development
cardiac muscle tissue regeneration
positive regulation of ERK1 and ERK2 cascade
positive regulation of STAT protein import into nucleus

Function(s)

protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
epidermal growth factor receptor binding
protein binding
ATP binding
protein homodimerization activity
transcription regulatory region DNA binding