192561

• Gene Symbol: Shank1
• Gene Name: SH3 and multiple ankyrin repeat domains 1
• Gene Aliases: Shank1a, Spank1, Sstrip
• Chromosome Location: Chr.1: 100297157 - 100344377 on Build Rnor_6.0
• UniGene ID: Rn.225968
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Shank1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031751.2	NP_113939.2	22	2680
	XM_008759414.1	XP_008757636.1	20	2723
	XM_008759415.1	XP_008757637.1	20	2720
	XM_008759416.1	XP_008757638.1	21	2747
	XM_008759417.1	XP_008757639.1	21	2747
GenBank mRNA	AF102855.2	-	20	2565
	AF131951.1	-	20	2577
	AF159046.1	-	22	2680

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001034115, AK078290.

Gene Ontology Categories:

Process(es)

protein complex assembly
cytoskeletal anchoring at plasma membrane
long-term memory
associative learning
adult behavior
negative regulation of actin filament bundle assembly
social behavior
protein localization to synapse
olfactory behavior
habituation
neuromuscular process controlling balance
determination of affect
righting reflex
synapse maturation
dendritic spine morphogenesis
positive regulation of dendritic spine development
vocalization behavior
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential

Function(s)

protein binding
protein C-terminus binding
SH3 domain binding
receptor signaling complex scaffold activity
GKAP/Homer scaffold activity
somatostatin receptor binding
protein complex binding
ionotropic glutamate receptor binding
identical protein binding
ankyrin repeat binding
scaffold protein binding