192639

• Gene Symbol: Hmga2
• Gene Name: high mobility group AT-hook 2
• Gene Aliases: Hmgic
• Chromosome Location: Chr.7: 65159944 - 65275408 on Build Rnor_6.0
• UniGene ID: Rn.29981
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hmga2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_032070.1	NP_114459.1	2	539
GenBank mRNA	U89695.1	-	2	539

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010441, X58380, BC052158, BC085085, BC069985, and others.

Panther Classification:

Molecular Function -

endodeoxyribonuclease

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA catabolic process, endonucleolytic
epithelial to mesenchymal transition
chondrocyte differentiation
mesodermal-endodermal cell signaling
base-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
mitotic G2 DNA damage checkpoint
signal transduction
spermatogenesis
cell proliferation
positive regulation of cell proliferation
male gonad development
response to virus
regulation of cell cycle process
positive regulation of gene expression
cell proliferation in forebrain
pituitary gland development
adrenal gland development
chromosome breakage
heterochromatin assembly
negative regulation of intracellular steroid hormone receptor signaling pathway
somatic stem cell population maintenance
histone H2A-S139 phosphorylation
senescence-associated heterochromatin focus assembly
endodermal cell differentiation
chondrocyte proliferation
positive regulation of multicellular organism growth
DNA damage response, detection of DNA damage
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of DNA binding
negative regulation by host of viral transcription
fat cell differentiation
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of JAK-STAT cascade
mesodermal cell differentiation
negative regulation of astrocyte differentiation
mesenchymal cell differentiation
stem cell differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of growth hormone secretion
adipose tissue development
fat pad development
positive regulation of cell cycle arrest
regulation of peptide hormone secretion
oncogene-induced cell senescence
regulation of stem cell population maintenance
positive regulation of stem cell proliferation
positive regulation of transcription regulatory region DNA binding
positive regulation of cellular response to X-ray
positive regulation of cellular senescence
positive regulation of response to DNA damage stimulus
negative regulation of double-strand break repair via nonhomologous end joining
regulation of cellular response to drug

Function(s)

regulatory region DNA binding
transcription factor activity, transcription factor binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
AT DNA binding
transcription factor activity, sequence-specific DNA binding
DNA-(apurinic or apyrimidinic site) lyase activity
DNA-dependent protein kinase activity
transcription factor binding
DNA binding, bending
enzyme binding
nucleosomal DNA binding
cAMP response element binding
MH2 domain binding
MH1 domain binding
SMAD binding
5'-deoxyribose-5-phosphate lyase activity
C2H2 zinc finger domain binding