193318

• Gene Symbol: Tcf3
• Gene Name: transcription factor 3
• Gene Aliases: Pan2, Tcfe2a
• Chromosome Location: Chr.7: 12146642 - 12168400 on Build Rnor_6.0
• UniGene ID: Rn.10290
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tcf3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001035237.1	NP_001030314.1	12	1106
	NM_133524.2	NP_598208.2	12	1106
GenBank mRNA	AJ973227.1	-	12	1106
	BC078750.1	-	12	1034	7123064
	X54549.1	-	12	1106
	X62323.1	-	12	1010

More Information

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
natural killer cell differentiation
B cell lineage commitment
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
gastrulation
positive regulation of gene expression
lymphocyte differentiation
positive regulation of B cell proliferation
response to lipopolysaccharide
T cell differentiation in thymus
immunoglobulin V(D)J recombination
response to drug
histone H3 acetylation
histone H4 acetylation
positive regulation of neuron differentiation
positive regulation of cell cycle
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell development
Peyer's patch development
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of G1/S transition of mitotic cell cycle

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
PDZ domain binding
mitogen-activated protein kinase kinase kinase binding
protein homodimerization activity
bHLH transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
protein dimerization activity
repressing transcription factor binding
vitamin D response element binding
E-box binding