195801

• Gene Symbol: Nlgn1
• Gene Name: neuroligin 1
• Gene Aliases: -
• Chromosome Location: Chr.2: 111057291 - 111792962 on Build Rnor_6.0
• UniGene ID: Rn.10173
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nlgn1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053868.2	NP_446320.1	2	611
GenBank mRNA	U22952.1	-	2	975

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001163387, NM_138666, BC005523, AK083116, AK122433.

Panther Classification:

Molecular Function -

cell adhesion molecule

Gene Ontology Categories:

Process(es)

regulation of respiratory gaseous exchange by neurological system process
protein targeting
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
neuron cell-cell adhesion
nervous system development
synapse assembly
metabolic process
positive regulation of circadian sleep/wake cycle, wakefulness
synaptic vesicle targeting
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
positive regulation of synaptic transmission, GABAergic
protein localization to synapse
neuronal ion channel clustering
establishment of protein localization
regulation of neuron differentiation
rhythmic process
cytoskeletal matrix organization at active zone
modulation of synaptic transmission
synapse organization
protein homooligomerization
protein heterotetramerization
positive regulation of filopodium assembly
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
inhibitory postsynaptic potential
positive regulation of dendritic spine development
terminal button organization
synaptic vesicle clustering
postsynaptic membrane assembly
presynaptic membrane assembly
AMPA glutamate receptor clustering
NMDA glutamate receptor clustering
neurexin clustering involved in presynaptic membrane assembly
postsynaptic density protein 95 clustering
receptor localization to synapse
positive regulation of ruffle assembly
positive regulation of synaptic vesicle endocytosis
positive regulation of intracellular signal transduction
positive regulation of synaptic vesicle exocytosis
regulation of N-methyl-D-aspartate selective glutamate receptor activity
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential

Function(s)

receptor activity
protein binding
PDZ domain binding
neurexin family protein binding
protein dimerization activity
cell adhesion molecule binding
carboxylic ester hydrolase activity