19582

• Gene Symbol: BACE1
• Gene Name: beta-secretase 1
• Gene Aliases: ASP2, BACE, HSPC104
• Chromosome Location: Chr.11: 117285686 - 117316256 on Build GRCh38
• UniGene ID: Hs.504003
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BACE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001207048.1	NP_001193977.1	2	209
	NM_001207049.1	NP_001193978.1	2	209
	NM_012104.4	NP_036236.1	3	847
	NM_138971.3	NP_620427.1	3	847
	NM_138972.3	NP_620428.1	3	847
	NM_138973.3	NP_620429.1	3	847
GenBank mRNA	AB032975.2	-	3	829
	AB050436.1	-	3	389
	AB050437.1	-	3	389
	AB050438.1	-	3	389
	AB177847.1	-	2	71
	AF190725.1	-	3	839
	AF200193.1	-	3	347
	AF200343.1	-	3	386
	AF201468.1	-	3	840
	AF204943.1	-	3	386
	AF338816.1	-	3	386
	AF338817.1	-	3	386
	AK075049.1	-	3	322
	AK296015.1	-	2	112
	AK296535.1	-	2	122
	BC036084.1	-	3	842	5311572
	BC065492.1	-	3	847	6538154
	DC343475.1	-	2	209

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001145947, NM_011792, AK080498, AF200346, AK041285, and others.

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
membrane protein ectodomain proteolysis
protein catabolic process
cellular protein metabolic process
beta-amyloid metabolic process

Function(s)

beta-amyloid binding
aspartic-type endopeptidase activity
protein binding
peptidase activity
beta-aspartyl-peptidase activity
enzyme binding