1960

• Gene Symbol: F2RL1
• Gene Name: F2R like trypsin receptor 1
• Gene Aliases: GPR11, PAR2
• Chromosome Location: Chr.5: 76819008 - 76835315 on Build GRCh38
• UniGene ID: Hs.744181
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: F2RL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017009223.1	XP_016864712.1	2	221
GenBank mRNA	AY336105.1	-	2	243
	BC012453.1	-	2	254	3857382
	BC018130.1	-	2	316	3895653
	BT009856.1	-	2	162
	DB463838.1	-	2	368
	U34038.1	-	2	309

More Information

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

T cell activation involved in immune response
positive regulation of leukocyte chemotaxis
positive regulation of cytokine secretion involved in immune response
positive regulation of glomerular filtration
inflammatory response
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood coagulation
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of phosphatidylinositol 3-kinase signaling
regulation of blood coagulation
positive regulation of cell migration
positive regulation of actin filament depolymerization
positive regulation of pseudopodium assembly
positive regulation of superoxide anion generation
positive regulation of toll-like receptor 2 signaling pathway
negative regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
positive regulation of Rho protein signal transduction
chemokine (C-C motif) ligand 2 secretion
neutrophil activation
regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of eosinophil degranulation
innate immune response
positive regulation of vasodilation
positive regulation of transcription from RNA polymerase II promoter
regulation of JNK cascade
negative regulation of JNK cascade
positive regulation of JNK cascade
interleukin-1 beta secretion
leukocyte migration
positive regulation of chemotaxis
positive regulation of positive chemotaxis
defense response to virus
positive regulation of phagocytosis, engulfment
establishment of endothelial barrier
positive regulation of ERK1 and ERK2 cascade
thrombin receptor signaling pathway
leukocyte proliferation
positive regulation of neutrophil mediated killing of gram-negative bacterium
interleukin-10 secretion
interferon-gamma secretion
chemokine secretion
negative regulation of chemokine secretion
mature conventional dendritic cell differentiation
positive regulation of renin secretion into blood stream
positive regulation of interleukin-8 secretion
positive regulation of interleukin-6 secretion

Function(s)

G-protein alpha-subunit binding
receptor activity
G-protein coupled receptor activity
receptor binding
protein binding
thrombin receptor activity
G-protein beta-subunit binding