196009

• Gene Symbol: Cdkn1a
• Gene Name: cyclin-dependent kinase inhibitor 1A
• Gene Aliases: Cip1, UV96, Waf1
• Chromosome Location: Chr.20: 6348422 - 6358864 on Build Rnor_6.0
• UniGene ID: Rn.10089
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Cdkn1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_080782.3	NP_542960.1	2	188
	XM_006256128.2	XP_006256190.1	2	252
GenBank mRNA	BC100620.1	-	2	188	7938247
	U24174.1	-	2	231

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001111099, NM_007669, BY206886, AK139306, AK149910, and others.

Panther Classification:

Molecular Function -

kinase inhibitor

Gene Ontology Categories:

Process(es)

regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
protein phosphorylation
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
cell cycle arrest
Ras protein signal transduction
regulation of mitotic cell cycle
negative regulation of cell proliferation
response to UV
response to toxic substance
response to organic substance
response to X-ray
response to organonitrogen compound
negative regulation of gene expression
response to organic cyclic compound
negative regulation of cell growth
positive regulation of B cell proliferation
organ regeneration
cellular response to extracellular stimulus
regulation of protein import into nucleus, translocation
cellular response to heat
negative regulation of phosphorylation
response to drug
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
positive regulation of programmed cell death
negative regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of protein kinase activity
response to arsenic-containing substance
positive regulation of fibroblast proliferation
response to glucocorticoid
response to corticosterone
regulation of cell cycle
response to hyperoxia
intestinal epithelial cell maturation
cellular response to ionizing radiation
cellular response to UV-B
mitotic cell cycle arrest
cellular senescence
negative regulation of G1/S transition of mitotic cell cycle
regulation of DNA biosynthetic process
positive regulation of reactive oxygen species metabolic process

Function(s)

cyclin-dependent protein serine/threonine kinase inhibitor activity
protein binding
cyclin-dependent protein kinase activating kinase activity
cyclin binding
ubiquitin protein ligase binding
protein complex binding