196921

• Gene Symbol: Rela
• Gene Name: v-rel avian reticuloendotheliosis viral oncogene homolog A
• Gene Aliases: NFkB
• Chromosome Location: Chr.1: 220992770 - 221003249 on Build Rnor_6.0
• UniGene ID: Rn.19480
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rela
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_199267.2	NP_954888.1	7	648
GenBank mRNA	AY307375.1	-	6	587
	BC079457.1	-	7	648	7121610

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009045, M61909, AK157076, AK154630, BC094053, and others.

Panther Classification:

Molecular Function -

Rel homology transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
liver development
hair follicle development
acetaldehyde metabolic process
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
defense response
inflammatory response
I-kappaB kinase/NF-kappaB signaling
aging
positive regulation of cell proliferation
response to mechanical stimulus
response to bacterium
organ morphogenesis
response to organic substance
response to inorganic substance
response to UV-B
positive regulation of Schwann cell differentiation
response to organic cyclic compound
cytokine-mediated signaling pathway
positive regulation of chondrocyte differentiation
response to muramyl dipeptide
response to lipopolysaccharide
response to progesterone
response to insulin
response to cobalamin
response to cytokine
response to muscle stretch
NIK/NF-kappaB signaling
negative regulation of protein catabolic process
response to drug
response to hydrogen peroxide
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to amino acid
response to morphine
positive regulation of interleukin-12 biosynthetic process
innate immune response
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of insulin receptor signaling pathway
regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
response to cAMP
cellular response to hydrogen peroxide
nucleotide-binding oligomerization domain containing 2 signaling pathway
response to interleukin-1
cellular response to lipopolysaccharide
cellular response to nicotine
cellular response to interleukin-1
cellular response to interleukin-6
cellular response to tumor necrosis factor
cellular response to peptide hormone stimulus
positive regulation of miRNA metabolic process
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
enzyme binding
protein kinase binding
ubiquitin protein ligase binding
protein complex binding
activating transcription factor binding
phosphate ion binding
identical protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
NF-kappaB binding
repressing transcription factor binding
ankyrin repeat binding