197097

Gene Symbol:

Egf LOC100910178

Gene Name:

epidermal growth factor

pro-epidermal growth factor-like

Gene Aliases:

-

-

Chromosome Location:

Chr.2: 235049350 - 235062491 on Build Rnor_6.0

Chromosome Location:

Chr.2: 68820605 - 68895943 on Build Rnor_6.0

UniGene ID:

Rn.6075

-

Species:

Rat

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Egf
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012842.1	NP_036974.1		597
GenBank mRNA	BC062030.1	-		582	5623849
	JX149564.1	-		441
	JX437943.1	-		441
	U04842.1	-		597

Gene Symbol: LOC100910178
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_008760814.1	XP_008759036.1	2	608
	XM_008760815.1	XP_008759037.1	2	607
	XM_008760816.1	XP_008759038.1	2	368

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010113, BC060741, AK085707, V00741, AK084927, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
angiogenesis
epidermal growth factor receptor signaling pathway
STAT protein import into nucleus
positive regulation of cell proliferation
positive regulation of peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
positive regulation of cerebellar granule cell precursor proliferation
positive regulation of catenin import into nucleus
intracellular signal transduction
positive regulation of phosphorylation
positive regulation of DNA binding
positive regulation of MAP kinase activity
positive regulation of epidermal growth factor-activated receptor activity
positive regulation of mitotic nuclear division
positive regulation of transcription, DNA-templated
branching morphogenesis of an epithelial tube
regulation of protein secretion
regulation of peptidyl-tyrosine phosphorylation
negative regulation of secretion
regulation of protein transport
mammary gland alveolus development
ERK1 and ERK2 cascade
regulation of calcium ion import
negative regulation of cholesterol efflux
positive regulation of hyaluronan biosynthetic process
regulation of protein localization to cell surface
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

epidermal growth factor receptor binding
calcium ion binding
growth factor activity