197152

• Gene Symbol: Mgmt
• Gene Name: O-6-methylguanine-DNA methyltransferase
• Gene Aliases: -
• Chromosome Location: Chr.1: 209237255 - 209464189 on Build Rnor_6.0
• UniGene ID: Rn.9836
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mgmt
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012861.1	NP_036993.1	5	722
GenBank mRNA	M76704.1	-	4	667
	S61804.1	-	5	722
	X54862.1	-	5	748

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008598, M84524, AK090389, AB092490, BC031888, and others.

Gene Ontology Categories:

Process(es)

DNA repair
DNA dealkylation involved in DNA repair
cellular response to DNA damage stimulus
response to toxic substance
response to organic cyclic compound
methylation
cellular response to oxidative stress
response to drug
regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to ethanol
positive regulation of DNA repair
response to folic acid
negative regulation of cell death
mammary gland epithelial cell differentiation
cellular response to organic cyclic compound
cellular response to ionizing radiation

Function(s)

damaged DNA binding
methylated-DNA-[protein]-cysteine S-methyltransferase activity
calcium ion binding
methyltransferase activity