197481

• Gene Symbol: Npm1
• Gene Name: nucleophosmin (nucleolar phosphoprotein B23, numatrin)
• Gene Aliases: B23NP
• Chromosome Location: Chr.10: 18080949 - 18091063 on Build Rnor_6.0
• UniGene ID: Rn.54537
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Npm1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012992.4	NP_037124.1	9, 10	852
GenBank mRNA	BC060579.1	-	9, 10	856	6888417
	BC088088.1	-	9, 10	842	7382200
	FQ213938.1	-	6, 7	496
	FQ215037.1	-	6, 7	496
	FQ216414.1	-	6, 7	496
	FQ220615.1	-	6, 7	498
	FQ221347.1	-	6, 7	496
	FQ225887.1	-	6, 7	512
	FQ227209.1	-	6, 7	496
	FQ229117.1	-	6, 7	493
	FQ229951.1	-	6, 7	491
	FQ230591.1	-	6, 7	496
	FQ230655.1	-	6, 7	498
	FQ233055.1	-	6, 7	496
	FQ234255.1	-	6, 7	496
	J03969.1	-	9, 10	805

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_002520, NM_199185, BC016716, AY740635, M28699, and others.

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

ribosomal large subunit export from nucleus
ribosomal small subunit export from nucleus
DNA repair
nucleosome assembly
rRNA export from nucleus
cell volume homeostasis
nucleocytoplasmic transport
centrosome cycle
cell aging
protein localization
positive regulation of cell proliferation
negative regulation of cell proliferation
regulation of centrosome duplication
positive regulation of centrosome duplication
negative regulation of centrosome duplication
cell growth
positive regulation of cellular biosynthetic process
protein destabilization
regulation of endodeoxyribonuclease activity
ribosomal large subunit biogenesis
ribosomal small subunit biogenesis
negative regulation of apoptotic process
positive regulation of catalytic activity
regulation of DNA damage response, signal transduction by p53 class mediator
regulation of neuron apoptotic process
negative regulation of protein kinase activity by regulation of protein phosphorylation
positive regulation of translation
positive regulation of DNA replication
positive regulation of protein kinase activity
regulation of centriole replication
negative regulation of mRNA splicing, via spliceosome
positive regulation of DNA metabolic process
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
protein homooligomerization
regulation of cell cycle
regulation of endoribonuclease activity
regulation of eIF2 alpha phosphorylation by dsRNA

Function(s)

DNA binding
transcription coactivator activity
RNA binding
protein kinase inhibitor activity
phosphatidylinositol-3,4,5-trisphosphate binding
rRNA binding
enzyme binding
protein kinase binding
Tat protein binding
histone binding
protein homodimerization activity
ribosomal large subunit binding
ribosomal small subunit binding
poly(A) RNA binding
protein heterodimerization activity
NF-kappaB binding
unfolded protein binding