19752

• Gene Symbol: DKK1
• Gene Name: dickkopf WNT signaling pathway inhibitor 1
• Gene Aliases: DKK-1, SK
• Chromosome Location: Chr.10: 52314281 - 52317657 on Build GRCh38
• UniGene ID: Hs.40499
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DKK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012242.2	NP_036374.1	3	615
GenBank mRNA	AF127563.1	-	3	600
	AF177394.1	-	3	563
	AK314902.1	-	3	613
	AY359005.1	-	3	598
	BC001539.2	-	3	600	3508222
	JN966744.1	-	3	644

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis involved in differentiation
endoderm formation
mesoderm formation
hair follicle development
regulation of receptor internalization
negative regulation of Wnt signaling pathway
embryonic limb morphogenesis
negative regulation of BMP signaling pathway
forebrain development
negative regulation of protein binding
response to retinoic acid
negative regulation of peptidyl-serine phosphorylation
negative regulation of mesodermal cell fate specification
regulation of endodermal cell fate specification
negative regulation of skeletal muscle tissue development
negative regulation of synapse assembly
regulation of synaptic transmission, glutamatergic
face morphogenesis
negative regulation of pathway-restricted SMAD protein phosphorylation
motor learning
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
extracellular negative regulation of signal transduction
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
regulation of dopaminergic neuron differentiation
midbrain morphogenesis
negative regulation of Wnt-Frizzled-LRP5/6 complex assembly
negative regulation of cardiac muscle cell differentiation

Function(s)

signal transducer activity
protein binding
growth factor activity
co-receptor binding
receptor antagonist activity
low-density lipoprotein particle receptor binding