197669

• Gene Symbol: Cd74
• Gene Name: Cd74 molecule, major histocompatibility complex, class II invariant chain
• Gene Aliases: INVG34
• Chromosome Location: Chr.18: 56071420 - 56080851 on Build Rnor_6.0
• UniGene ID: Rn.33804
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Cd74
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013069.2	NP_037201.1	7, 8	728
	XM_006254761.2	XP_006254823.1	8, 9	978
GenBank mRNA	BC059152.1	-	7, 8	709	6890709
	FQ219430.1	-	7, 8	711
	FQ225098.1	-	7, 8	703
	FQ225666.1	-	5, 6	347
	FQ227357.1	-	7, 8	706
	FQ227455.1	-	7, 8	708
	FQ227561.1	-	7, 8	712
	FQ228116.1	-	7, 8	711
	FQ231756.1	-	7, 8	712
	FQ232412.1	-	7, 8	753
	FQ232423.1	-	7, 8	742
	FQ232867.1	-	7, 8	712
	FQ232996.1	-	7, 8	705
	FQ233568.1	-	7, 8	711
	FQ233706.1	-	7, 8	711
	FQ234457.1	-	7, 8	714
	X13044.1	-	7, 8	684
	X14254.1	-	8, 9	884

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

activation of MAPK activity
prostaglandin biosynthetic process
positive regulation of cytokine-mediated signaling pathway
positive regulation of dendritic cell antigen processing and presentation
negative regulation of peptide secretion
positive regulation of type 2 immune response
negative regulation of mature B cell apoptotic process
protein complex assembly
intracellular protein transport
defense response
signal transduction
cell proliferation
immunoglobulin mediated immune response
cytokine-mediated signaling pathway
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
positive regulation of B cell proliferation
macrophage migration inhibitory factor signaling pathway
negative regulation of apoptotic process
negative regulation of DNA damage response, signal transduction by p53 class mediator
positive thymic T cell selection
negative thymic T cell selection
negative regulation of T cell differentiation
positive regulation of T cell differentiation
positive regulation of fibroblast proliferation
positive regulation of peptidyl-tyrosine phosphorylation
chaperone mediated protein folding requiring cofactor
positive regulation of macrophage cytokine production
positive regulation of ERK1 and ERK2 cascade
positive regulation of neutrophil chemotaxis
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of chemokine (C-X-C motif) ligand 2 production

Function(s)

beta-amyloid binding
cytokine receptor activity
cytokine binding
MHC class II protein complex binding
macrophage migration inhibitory factor binding
MHC class II protein binding
MHC class II protein binding, via antigen binding groove
protein binding involved in protein folding
nitric-oxide synthase binding