19768

• Gene Symbol: BACE1
• Gene Name: beta-secretase 1
• Gene Aliases: ASP2, BACE, HSPC104
• Chromosome Location: Chr.11: 117285686 - 117316256 on Build GRCh38
• UniGene ID: Hs.504003
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BACE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001207048.1	NP_001193977.1	4, 5	668
	NM_001207049.1	NP_001193978.1	4, 5	593
	NM_012104.4	NP_036236.1	5, 6	1306
	NM_138971.3	NP_620427.1	5, 6	1174
	NM_138972.3	NP_620428.1	5, 6	1231
	NM_138973.3	NP_620429.1	5, 6	1099
GenBank mRNA	AB032975.2	-	5, 6	1288
	AB050436.1	-	5, 6	773
	AB050437.1	-	5, 6	716
	AB050438.1	-	5, 6	641
	AB177847.1	-	4, 5	530
	AF161367.1	-	1, 2	134
	AF190725.1	-	5, 6	1298
	AF200193.1	-	5, 6	806
	AF200343.1	-	5, 6	845
	AF201468.1	-	5, 6	1299
	AF204943.1	-	5, 6	845
	AF338816.1	-	5, 6	770
	AF338817.1	-	5, 6	713
	AK075049.1	-	5, 6	781
	AK296015.1	-	4, 5	496
	AK296535.1	-	4, 5	581
	BC036084.1	-	5, 6	1301	5311572
	BC065492.1	-	5, 6	1306	6538154

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019204, AF190727.

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
membrane protein ectodomain proteolysis
protein catabolic process
cellular protein metabolic process
beta-amyloid metabolic process

Function(s)

beta-amyloid binding
aspartic-type endopeptidase activity
protein binding
peptidase activity
beta-aspartyl-peptidase activity
enzyme binding