198005

• Gene Symbol: Eif2ak1
• Gene Name: eukaryotic translation initiation factor 2 alpha kinase 1
• Gene Aliases: Hri
• Chromosome Location: Chr.12: 12749026 - 12782078 on Build Rnor_6.0
• UniGene ID: Rn.3333
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Eif2ak1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013223.1	NP_037355.1	5	504
GenBank mRNA	BC081838.1	-	5	537	7132671
	L27707.1	-	5	504

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_013557, AK173160, AK155206, BC028923, AK158437, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

acute inflammatory response
translational initiation
regulation of translation
protein phosphorylation
phagocytosis
negative regulation of cell proliferation
regulation of translational initiation by eIF2 alpha phosphorylation
regulation of eIF2 alpha phosphorylation by heme
macrophage differentiation
negative regulation of translational initiation
protoporphyrinogen IX metabolic process
protein autophosphorylation
regulation of hemoglobin biosynthetic process
negative regulation of hemoglobin biosynthetic process
iron ion homeostasis

Function(s)

protein kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
ATP binding
heme binding
protein homodimerization activity