198954

• Gene Symbol: Flt1
• Gene Name: FMS-related tyrosine kinase 1
• Gene Aliases: VEGFR-1
• Chromosome Location: Chr.12: 9033998 - 9203771 on Build Rnor_6.0
• UniGene ID: Rn.10239
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Flt1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019306.1	NP_062179.1	4	638
	XM_008768998.1	XP_008767220.1	4	1048
GenBank mRNA	AF157595.1	-	4	402
	D28498.1	-	4	638

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010228, L07297, AK146906, D88690, AK167596, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
angiogenesis
patterning of blood vessels
response to hypoxia
sprouting angiogenesis
monocyte chemotaxis
protein phosphorylation
chemotaxis
regulation of smooth muscle contraction
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cell proliferation
positive regulation of phospholipase C activity
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
peptidyl-tyrosine phosphorylation
signal transduction by protein phosphorylation
cell differentiation
positive regulation of cell migration
intracellular receptor signaling pathway
positive regulation of vascular endothelial growth factor receptor signaling pathway
vascular endothelial growth factor receptor-1 signaling pathway
vascular endothelial growth factor signaling pathway
positive regulation of MAP kinase activity
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of angiogenesis
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
positive regulation of fibroblast proliferation
blood vessel morphogenesis
embryonic morphogenesis
positive regulation of smooth muscle cell proliferation

Function(s)

transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
ATP binding
growth factor binding
VEGF-A-activated receptor activity
VEGF-B-activated receptor activity
placental growth factor-activated receptor activity
identical protein binding