199069

• Gene Symbol: Egln3
• Gene Name: egl-9 family hypoxia-inducible factor 3
• Gene Aliases: PHD-3, PHD3, SM-20
• Chromosome Location: Chr.6: 75050329 - 75075795 on Build Rnor_6.0
• UniGene ID: Rn.10994
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Egln3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019371.1	NP_062244.1	4	1207
GenBank mRNA	U06713.1	-	4	1207

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_022073, AJ310545, BC105938, BC105939, AK026918, and others.
This siRNA also targets the following transcripts in Mouse: NM_028133, BC044926, AJ310548, AF421882, AK044787, and others.

Gene Ontology Categories:

Process(es)

response to hypoxia
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
protein hydroxylation
peptidyl-proline hydroxylation to 4-hydroxy-L-proline
peptidyl-proline hydroxylation
regulation of cell proliferation
regulation of neuron apoptotic process
oxidation-reduction process

Function(s)

iron ion binding
protein binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
L-ascorbic acid binding
peptidyl-proline dioxygenase activity
peptidyl-proline 4-dioxygenase activity