199498

• Gene Symbol: Nr1h3
• Gene Name: nuclear receptor subfamily 1, group H, member 3
• Gene Aliases: LXRalpha
• Chromosome Location: Chr.3: 80004130 - 80014197 on Build Rnor_6.0
• UniGene ID: Rn.11209
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nr1h3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031627.2	NP_113815.2	9	1581
	XM_006234533.2	XP_006234595.1	10	1759
	XM_006234534.1	XP_006234596.1	10	1700
	XM_006234535.2	XP_006234597.1	10	1901
	XM_006234537.1	XP_006234599.1	9	1371
	XM_008762013.1	XP_008760235.1	9	1491
GenBank mRNA	BC088750.1	-	9	1581	7314121
	U11685.1	-	9	1588

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001177730, NM_013839, AK159250, AK143904, BC012646, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
lipid metabolic process
insulin receptor signaling pathway
positive regulation of triglyceride biosynthetic process
positive regulation of receptor biosynthetic process
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
intracellular receptor signaling pathway
positive regulation of cellular protein metabolic process
negative regulation of lipid transport
positive regulation of cholesterol transport
response to progesterone
positive regulation of toll-like receptor 4 signaling pathway
cholesterol homeostasis
negative regulation of macrophage activation
apoptotic cell clearance
steroid hormone mediated signaling pathway
cellular lipid metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of pinocytosis
negative regulation of inflammatory response
positive regulation of lipoprotein lipase activity
lipid homeostasis
sterol homeostasis
triglyceride homeostasis
cellular response to lipopolysaccharide
negative regulation of pancreatic juice secretion
negative regulation of secretion of lysosomal enzymes
regulation of cholesterol homeostasis
positive regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
zinc ion binding
sterol response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
retinoid X receptor binding
protein heterodimerization activity