199668

• Gene Symbol: Crebbp
• Gene Name: CREB binding protein
• Gene Aliases: CBP, RSTS, RTS
• Chromosome Location: Chr.10: 11594914 - 11721039 on Build Rnor_6.0
• UniGene ID: Rn.12815
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Crebbp
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_133381.3	NP_596872.3	1, 2	111
	XM_008767524.1	XP_008765746.1	1, 2	241
GenBank mRNA	AB066219.1	-	1, 2	88
	AY462245.1	-	1, 2	111

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_004380, NM_001079846, AB210043, U85962, U47741.

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell proliferation
histone acetylation
N-terminal peptidyl-lysine acetylation
germ-line stem cell population maintenance
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
response to interleukin-1
positive regulation of G1/S transition of mitotic cell cycle

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
p53 binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
transcription factor binding
zinc ion binding
acetyltransferase activity
activating transcription factor binding
peroxisome proliferator activated receptor binding
MRF binding
SMAD binding