199770

• Gene Symbol: Apc
• Gene Name: adenomatous polyposis coli
• Gene Aliases: RATAPC
• Chromosome Location: Chr.18: 27011706 - 27106323 on Build Rnor_6.0
• UniGene ID: Rn.156346
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Apc
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012499.1	NP_036631.1	1	139
	XM_006254508.2	XP_006254570.1	2	186
	XM_006254509.2	XP_006254571.1	2	155
	XM_006254511.2	XP_006254573.1	2	186
	XM_006254521.2	XP_006254583.1	2	186
	XM_008772015.1	XP_008770237.1	1	33
GenBank mRNA	D38629.1	-	1	139

More Information

Gene Ontology Categories:

Process(es)

mitotic cytokinesis
kidney development
hair follicle development
protein complex assembly
cellular response to DNA damage stimulus
negative regulation of microtubule depolymerization
cell cycle arrest
metaphase/anaphase transition of mitotic cell cycle
mitotic spindle assembly checkpoint
establishment or maintenance of cell polarity
pattern specification process
axonogenesis
negative regulation of cell proliferation
axis specification
anterior/posterior pattern specification
dorsal/ventral pattern formation
proximal/distal pattern formation
Wnt signaling pathway
cell migration
stem cell population maintenance
negative regulation of Wnt signaling pathway
regulation of cell migration
positive regulation of cell migration
regulation of epithelial cell differentiation
positive regulation of epithelial cell differentiation
pancreas development
positive regulation of microtubule polymerization
cytoplasmic microtubule organization
neuron projection development
positive regulation of pseudopodium assembly
regulation of microtubule-based process
T cell differentiation in thymus
somatic stem cell population maintenance
negative regulation of odontogenesis
response to drug
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of MAPK cascade
skin development
canonical Wnt signaling pathway involved in negative regulation of apoptotic process
canonical Wnt signaling pathway involved in positive regulation of apoptotic process
regulation of cell differentiation
positive regulation of cell differentiation
regulation of osteoblast differentiation
regulation of osteoclast differentiation
positive regulation of protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of cell adhesion
muscle cell cellular homeostasis
thymus development
negative regulation of epithelial cell proliferation
regulation of nitrogen compound metabolic process
chromosome organization
regulation of cell cycle
positive regulation of cell division
regulation of attachment of spindle microtubules to kinetochore
retina development in camera-type eye
canonical Wnt signaling pathway
negative regulation of epithelial cell proliferation involved in prostate gland development
negative regulation of canonical Wnt signaling pathway
response to alcohol
cellular response to nerve growth factor stimulus
regulation of glutamate metabolic process

Function(s)

protease binding
protein binding
beta-catenin binding
microtubule binding
protein kinase regulator activity
protein kinase binding
protein complex binding
gamma-catenin binding
cadherin binding
microtubule plus-end binding