200364

• Gene Symbol: Fyn
• Gene Name: FYN proto-oncogene, Src family tyrosine kinase
• Gene Aliases: -
• Chromosome Location: Chr.20: 44436354 - 44630316 on Build Rnor_6.0
• UniGene ID: Rn.19361
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fyn
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012755.1	NP_036887.1	8, 9	925
	XM_006256520.2	XP_006256582.1	6, 7	1760
	XM_006256522.1	XP_006256584.1	7, 8	1212
GenBank mRNA	U35365.1	-	8, 9	925

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001122893, AK156584, BQ179147, AK188892.

Gene Ontology Categories:

Process(es)

neuron migration
protein phosphorylation
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
central nervous system development
regulation of cell shape
negative regulation of gene expression
positive regulation of neuron projection development
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
peptidyl-tyrosine phosphorylation
cell differentiation
forebrain development
negative regulation of protein ubiquitination
ionotropic glutamate receptor signaling pathway
cellular response to platelet-derived growth factor stimulus
peptidyl-tyrosine autophosphorylation
T cell activation
regulation of cell proliferation
negative regulation of protein catabolic process
response to drug
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of neuron apoptotic process
innate immune response
response to ethanol
protein autophosphorylation
dendrite morphogenesis
activated T cell proliferation
T cell receptor signaling pathway
detection of mechanical stimulus involved in sensory perception of pain
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to transforming growth factor beta stimulus
positive regulation of protein localization to nucleus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

G-protein coupled receptor binding
glycoprotein binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
tubulin binding
protein complex binding
T cell receptor binding
CD4 receptor binding
CD8 receptor binding
phosphatidylinositol 3-kinase binding
ion channel binding
metal ion binding
ephrin receptor binding
peptide hormone receptor binding
growth factor receptor binding