200382

• Gene Symbol: Casp1
• Gene Name: caspase 1
• Gene Aliases: Ice, Il1bc
• Chromosome Location: Chr.8: 2605743 - 2614637 on Build Rnor_6.0
• UniGene ID: Rn.37508
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Casp1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012762.2	NP_036894.2	2	291
GenBank mRNA	D85899.1	-	2	291
	U14647.1	-	2	291

More Information

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

response to hypoxia
microglial cell activation
proteolysis
apoptotic process
midgut development
myoblast fusion
memory
response to bacterium
response to toxic substance
regulation of autophagy
response to organic cyclic compound
protein processing
lung development
response to lipopolysaccharide
interleukin-1 beta production
response to ATP
response to drug
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of circadian sleep/wake cycle, non-REM sleep
positive regulation of cytokine secretion
positive regulation of interleukin-1 alpha secretion
positive regulation of interleukin-1 beta secretion
regulation of inflammatory response
mitochondrial depolarization
membrane hyperpolarization
pyroptosis
cellular response to mechanical stimulus
cellular response to organic substance
execution phase of apoptosis
programmed necrotic cell death
toxin transport

Function(s)

endopeptidase activity
cysteine-type endopeptidase activity
protein binding
peptidase activity
scaffold protein binding