200440

• Gene Symbol: Dlg1
• Gene Name: discs, large homolog 1 (Drosophila)
• Gene Aliases: Dlgh1, SAP97
• Chromosome Location: Chr.11: 72164566 - 72378895 on Build Rnor_6.0
• UniGene ID: Rn.89331
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dlg1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012788.1	NP_036920.1	3	591
GenBank mRNA	U14950.1	-	3	591

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001098424, NM_001204386, NM_004087, U13897, BC028486, and others.
This siRNA also targets the following transcripts in Mouse: NM_007862, NM_001252434, NM_001252433, NM_001252435, BC047142, and others.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

ureteric bud development
branching involved in ureteric bud morphogenesis
immunological synapse formation
endothelial cell proliferation
lens development in camera-type eye
T cell cytokine production
actin filament organization
cell adhesion
chemical synaptic transmission
nervous system development
protein localization
positive regulation of cell proliferation
single organismal cell-cell adhesion
peristalsis
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
membrane raft organization
regulation of myelination
activation of protein kinase activity
regulation of protein localization
T cell activation
negative regulation of T cell proliferation
regulation of membrane potential
amyloid precursor protein metabolic process
receptor clustering
positive regulation of potassium ion transport
establishment or maintenance of epithelial cell apical/basal polarity
negative regulation of mitotic cell cycle
nucleotide phosphorylation
reproductive structure development
embryonic skeletal system morphogenesis
tissue morphogenesis
smooth muscle tissue development
negative regulation of epithelial cell proliferation
negative regulation of protein kinase B signaling
hard palate development
bicellular tight junction assembly
protein localization to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
receptor localization to synapse

Function(s)

guanylate kinase activity
protein binding
protein C-terminus binding
potassium channel regulator activity
protein kinase binding
phosphatase binding
PDZ domain binding
mitogen-activated protein kinase kinase binding
protein complex scaffold
ionotropic glutamate receptor binding
ion channel binding
L27 domain binding