200569

• Gene Symbol: Erbb2
• Gene Name: v-erb-b2 avian erythroblastic leukemia viral oncogene 2
• Gene Aliases: -
• Chromosome Location: Chr.10: 86367596 - 86391728 on Build Rnor_6.0
• UniGene ID: Rn.93966
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Erbb2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017003.2	NP_058699.2	3, 4	548
GenBank mRNA	AY116182.1	-	3, 4	548
	X03362.1	-	3, 4	459

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001003817, CF728071, AK129487, BC053078, AK083669, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

liver development
positive regulation of protein phosphorylation
transcription, DNA-templated
signal transduction
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
nervous system development
central nervous system development
peripheral nervous system development
heart development
skeletal muscle tissue development
neuromuscular junction development
motor neuron axon guidance
positive regulation of cell proliferation
glial cell differentiation
phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
signal transduction by protein phosphorylation
positive regulation of cell growth
response to progesterone
regulation of microtubule-based process
negative regulation of immature T cell proliferation in thymus
wound healing
regulation of cell proliferation
response to drug
myelination
negative regulation of apoptotic process
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
tongue development
estrous cycle
regulation of cell differentiation
positive regulation of translation
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase I promoter
positive regulation of transcription from RNA polymerase III promoter
positive regulation of Ras protein signal transduction
protein autophosphorylation
sympathetic nervous system development
response to axon injury
oligodendrocyte differentiation
positive regulation of epithelial cell proliferation
mammary gland involution
regulation of ERK1 and ERK2 cascade

Function(s)

RNA polymerase I core binding
glycoprotein binding
DNA binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
transmembrane signaling receptor activity
protein binding
ATP binding
protein C-terminus binding
growth factor binding
protein phosphatase binding
ubiquitin protein ligase binding
identical protein binding
protein heterodimerization activity
Hsp90 protein binding