201083

• Gene Symbol: Ascl2
• Gene Name: achaete-scute family bHLH transcription factor 2
• Gene Aliases: -
• Chromosome Location: Chr.1: 216154002 - 216156409 on Build Rnor_6.0
• UniGene ID: Rn.10486
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ascl2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031503.2	NP_113691.1	3	1243
GenBank mRNA	X53724.1	-	3	1187

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008554, CJ215499, BC019520, AK167324, AK010738.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
in utero embryonic development
placenta development
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
negative regulation of Schwann cell proliferation
cell differentiation
somatic stem cell population maintenance
spongiotrophoblast differentiation
spongiotrophoblast layer development

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
protein dimerization activity
E-box binding