201105

• Gene Symbol: Kras
• Gene Name: Kirsten rat sarcoma viral oncogene
• Gene Aliases: Kras2, c-Ki-ras, p21
• Chromosome Location: Chr.4: 179483086 - 179515609 on Build Rnor_6.0
• UniGene ID: Rn.24554
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Kras
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031515.3	NP_113703.1	3	320
	XM_008763352.1	XP_008761574.1	3	2913
	XM_008763353.1	XP_008761575.1	4	357
	XM_008763354.1	XP_008761576.1	4	502
	XM_008763355.1	XP_008761577.1	3	2913
GenBank mRNA	BC126086.1	-	4	458	8362025
	FQ230946.1	-	4	501
	U09793.1	-	3	320

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_021284, BC004642, AK155064, AK164065, BC010202, and others.

Panther Classification:

Molecular Function -

small GTPase

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
small GTPase mediated signal transduction
Ras protein signal transduction
positive regulation of cell proliferation
visual learning
positive regulation of gene expression
cytokine-mediated signaling pathway
actin cytoskeleton organization
regulation of synaptic transmission, GABAergic
positive regulation of Rac protein signal transduction
social behavior
positive regulation of MAP kinase activity
negative regulation of neuron apoptotic process
negative regulation of cell differentiation
regulation of long-term neuronal synaptic plasticity
homeostasis of number of cells within a tissue
positive regulation of nitric-oxide synthase activity
positive regulation of NF-kappaB transcription factor activity
striated muscle cell differentiation
response to glucocorticoid
response to mineralocorticoid
epithelial tube branching involved in lung morphogenesis

Function(s)

GTPase activity
protein binding
GTP binding
GMP binding
GDP binding
LRR domain binding
protein complex binding