201157

• Gene Symbol: Brca2
• Gene Name: breast cancer 2, early onset
• Gene Aliases: -
• Chromosome Location: Chr.12: 504007 - 544754 on Build Rnor_6.0
• UniGene ID: Rn.103225
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Brca2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031542.2	NP_113730.2	2, 3	250
GenBank mRNA	U89653.1	-	2, 3	249

More Information

Panther Classification:

Molecular Function -

damaged DNA-binding protein

Gene Ontology Categories:

Process(es)

double-strand break repair via homologous recombination
oocyte maturation
inner cell mass cell proliferation
nucleotide-excision repair
double-strand break repair
DNA recombination
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
male meiosis I
spermatogenesis
brain development
cell aging
response to nutrient
cell proliferation
female gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
response to X-ray
response to UV-C
response to gamma radiation
hemopoiesis
mammary gland development
homologous chromosome orientation involved in meiotic metaphase I plate congression
response to estradiol
regulation of cytokinesis
negative regulation of mammary gland epithelial cell proliferation
multicellular organism growth
regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
chordate embryonic development
histone H3 acetylation
histone H4 acetylation
positive regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
replication fork protection
chromosome organization
centrosome duplication

Function(s)

protease binding
single-stranded DNA binding
histone acetyltransferase activity
protein binding
H3 histone acetyltransferase activity
H4 histone acetyltransferase activity
gamma-tubulin binding