20998

• Gene Symbol: EXOSC2
• Gene Name: exosome component 2
• Gene Aliases: RRP4, Rrp4p, hRrp4p, p7
• Chromosome Location: Chr.9: 130693760 - 130704894 on Build GRCh38
• UniGene ID: Hs.654643
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EXOSC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001282708.1	NP_001269637.1	3, 4	310
	NM_014285.6	NP_055100.2	3, 4	310
	NR_104230.1		3, 4	310
	XM_005272176.2	XP_005272233.1	3, 4	308
GenBank mRNA	AK001916.1	-	3, 4	299
	AK022460.1	-	3, 4	296
	AK296605.1	-	3, 4	299
	AK303163.1	-	3, 4	290
	BC000747.2	-	3, 4	280	2821702
	BU934039.1	-		313

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_144886, BC021485, BC021807, AK166881, AK144234, and others.

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
positive regulation of cell growth
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
U4 snRNA 3'-end processing
regulation of mRNA stability
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
CUT catabolic process
nuclear polyadenylation-dependent rRNA catabolic process
nuclear polyadenylation-dependent tRNA catabolic process
nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription
polyadenylation-dependent snoRNA 3'-end processing

Function(s)

3'-5'-exoribonuclease activity
exoribonuclease activity
protein binding
7S RNA binding